To trouble aggressively, to harass.
To annoy, irritate.
To cause (mental) suffering to; to distress.
To twist, to weave.
To be irritated; to fret.
To toss back and forth; to agitate; to disquiet.
Annoyed, irritated or distressed
She became more and more vexed as she struggled to cope with the demands of the job.
Much debated, discussed or disputed