To pinch and pull with a sudden jerk and twist; to twitch.
to tweak the nose.
To adjust slightly; to fine-tune.
If we tweak the colors towards blue, it will look more natural.
To twit or tease.
To abuse methamphetamines, especially crystal meth.
To exhibit symptoms of methamphetamine abuse, such as extreme nervousness, compulsiveness, erratic motion, excitability; possibly a blend of twitch and freak.
To exhibit extreme nervousness, evasiveness when confronted by law enforcement or other authority (e.g., customs agents, border patrol, teacher, etc.), mimicking methamphetamine abuse symptoms.
Hallucinating, especially under the influence of crystal meth or similar narcotics.