A person who talks, especially one who gives a speech, or is loquacious or garrulous.
That guy's a real talker.
Any creature or machine that talks.
Some parrots are vociferous talkers.
A talk show
A talk-show host.
An all-talk radio station.
A popular topic of conversation.
The royal engagement is likely to be a top talker right through the wedding.
A talking point.
A stripped-down version of a MUD which is designed for talking, predating instant messengers; a kind of early chat room.
Mouth.