To shed (skin).
Snakes slough their skin periodically.
To slide off (like a layer of skin).
A week after he was burned, a layer of skin on his arm sloughed off.
To discard.
East sloughed a heart.
(Western US) To commit truancy, be absent from school without permission. (compare ditch)
"Dude, Kaydn and Jarom are totally sloughing today!"
Something sloughed off.
The act of casting off the skin or shell; ecdysis.