To hurt; to put to bodily uneasiness or anguish; to afflict with uneasy sensations of any degree of intensity; to torment; to torture.
The wound pained him.
To render uneasy in mind; to disquiet; to distress; to grieve.
It pains me to say that I must let you go.
To inflict suffering upon as a penalty; to punish.
In pain, especially in an emotional sense.