To make greatly distressed and/or a discomposed appearance
To be placed or place someone under the influence of a psychedelic drug
To streak; to variegate
To experience reality withdrawal, or hallucinations (nightmarish), to behave irrational or unconventional due to drug use.
To react extremely or irrationally, usually under distress or discomposure
A streak or variegation in a pattern.
(minced oath) Fucking.
You're getting on my freaking nerves!
Freakish.
Fucking.
He was so scared he freaking ran into a police station.