To (cause to) unravel; used particularly for the edge of something made of cloth, or the end of a rope.
The ribbon frayed at the cut end.
To cause exhaustion, wear out (a person's mental strength).
The hectic day ended in frayed nerves. (Metaphorical use; nerves are visualised as strings)
Frighten; alarm
To bear the expense of; to defray.
To rub.
Frayed material.
Any frayings of rope should be removed.
The skin which a deer frays from its horns.