To perplex or puzzle.
To fail to see the difference; to mix up; to confuse right and wrong.
To make something worse.
Don't confound the situation by yelling.
To combine in a confused fashion; to mingle so as to make the parts indistinguishable.
To cause to be ashamed; to abash.
His actions confounded the skeptics.
To defeat, to frustrate, to thwart.
To damn (a mild oath).
Confound the lady!
To bring to ruination.
To stun, amaze
The act by which things are confounded, or confused.
The process by which an apparent association between an exposure and an outcome is actually explained by another factor.